V-Tech System (Promoitalia) — PDRN serum vials and gel mask, Paramed Baku

Promoitalia, Italy PDRN 20 mg/ml Synthetic exosomal structures Protocol 4 × 14 days Price at consultation

V-Tech System (Promoitalia) — exosomal skin therapy in Baku

An Italian system by Promoitalia: synthetic exosomal structures, high-molecular-weight PDRN at 20 mg/ml and biomimetic peptides, plus a recovery mask applied straight after the session.

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Overview

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V-Tech System is developed by the Italian company Promoitalia. It comes in two parts: a serum and a mask applied immediately after the session. The serum is built on synthetic exosomal structures, high-molecular-weight polydeoxyribonucleotide (PDRN, around 2500 kDa) at 20 mg/ml, and biomimetic peptides. The mask contains hyaluronic acid and plant stem cells for hydration and bio-restructuring, plus polysaccharide fractions that damp down the inflammatory response. It is delivered transdermally through microneedling; the working areas are face, neck, hands and feet. The standard protocol is 4 sessions at 14-day intervals.

Benefits

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✅ Hydration and barrier repair without adding volume or heaviness
✅ Anti-inflammatory and antioxidant profile thanks to PDRN
✅ Skin density and tone over a course
✅ Suitable for hands and neck — areas where injections are tolerated less well
✅ Transdermal delivery: no injection papules and a short recovery

How it works

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The skin is cleansed and disinfected, and topical anaesthetic is applied for 20 minutes if needed. The serum is spread over the area and delivered transdermally with microneedling at a depth chosen for the zone. Immediately afterwards a mask with hyaluronic acid and plant stem cells is left on for 15–20 minutes, followed by a soothing product and SPF. A face session takes 45–60 minutes.

Technology

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One detail worth stating plainly: V-Tech uses synthetic exosomal structures, not exosomes isolated from human cells. It is a biomimetic carrier — it reproduces the principle of vesicular delivery of actives into the skin, but it is not a cell-derived product like ExoCoBio or BENEV. The main workload in the formula is carried by PDRN: high-molecular-weight polydeoxyribonucleotides at 20 mg/ml, the same class of active found in polynucleotide skin boosters, with a well-documented anti-inflammatory and regenerative profile. The biomimetic peptides add targeted signalling, and the post-procedure mask reduces skin reactivity and closes the microchannels.

Promoitalia — Italian manufacture
Synthetic exosomal structures (a biomimetic carrier, not a cell-derived product)
High-molecular-weight PDRN (~2500 kDa) at 20 mg/ml
Biomimetic peptides in the serum
Post-procedure mask: HA + plant stem cells + polysaccharides
Areas: face, neck, hands, feet
Protocol: 4 sessions at 14-day intervals

Preparation & aftercare

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Before the procedure

No active peels, scrubs or aggressive skincare for 3 days
Avoid aspirin and ibuprofen for 5–7 days (after clearing it with your doctor)
No alcohol for 24 hours
Do not come with active herpes, inflammation or a cold
No sunbathing or self-tanner before the session

After the procedure

No hot water or make-up for the first 24 hours
Sauna, steam room, pool and sport — after 3–5 days
SPF 30+ for at least 2 weeks
No acids or retinoids for 5–7 days
No other injectable procedures for 7–10 days

FAQ

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? How much does V-Tech System cost? ⌄

In the price list the item is marked "$$$" — we quote it at consultation: the cost depends on the area (face, face + neck, hands) and on whether the session runs on its own or together with RF microneedling. We can give you the exact figure on WhatsApp.

? Are these real exosomes? ⌄

Formally, no: the manufacturer declares synthetic exosomal structures — a biomimetic carrier that reproduces the principle of vesicular delivery. Cell-derived exosomes are ExoCoBio and BENEV, which are separate items in the price list.

? How does V-Tech differ from polynucleotides? ⌄

The actives are close: V-Tech is built on high-molecular-weight PDRN at 20 mg/ml. The difference is delivery — polynucleotides are injected, V-Tech is applied transdermally through microneedling, so there are no papules and recovery is shorter.

? How many sessions are needed? ⌄

The manufacturer's protocol is 4 sessions at 14-day intervals, followed by maintenance every 2–3 months depending on the skin.

? Can it be done on the hands and neck? ⌄

Yes — that is one of the system's strengths: the manufacturer specifically lists face, neck, hands and feet. For hands it is a convenient option, as injection protocols are harder to tolerate there.

Booking

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Ready to start?

Book a consultation — the doctor will assess your skin and tell you whether V-Tech System is right for you or another protocol makes more sense.

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Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

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AZN Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

Service

Price

Dives AXC1000 (exosomes — hair or face)

Exosomal modulator: exosomes + hyaluronic acid + polynucleotides. Mesotherapy/microneedling.

200–260 AZN

ExoCoBio ASCE+ SRLV (face)

Premium flagship. Used at Oracle, Wonjin, Banobagi after laser resurfacing and microneedling.

480–550 AZN

ExoCoBio Exomage (face, sensitive skin / rosacea)

Anti-inflammatory profile; for rosacea, couperose and reactive skin.

500–580 AZN

BENEV Exosomes (face)

Premium; exosomes from umbilical stem cells. Standard partner for microneedling and RF.

450–520 AZN

Exosomes for face — standard kit

Affordable option for basic protocols and maintenance courses.

350–400 AZN

V-Tech System (Promoitalia) — face, neck, hands

Italy, Promoitalia. Synthetic exosomal structures + high-molecular-weight PDRN (20 mg/ml) + biomimetic peptides; the kit includes a mask with hyaluronic acid and plant stem cells. Applied via microneedling: face, neck, hands, feet. Protocol — 4 sessions at 14-day intervals.

$$$

ExoCoBio ASCE for hair

Premium kit: 10 billion exosomes + biotin + 1008 growth factors. Korean flagship.

380–450 AZN

BENEV Exosomes for hair

Premium kit; exosomes from umbilical stem cells. Pairs well with microneedling and RF.

350–420 AZN

Exosomes for hair — standard kit

Affordable option for maintenance courses; alternative certified kits.

250–300 AZN

Zishel Xomage H (Korea) — hair and scalp

Korea, Zishel Medical. 10 billion particles per vial: adipose-derived mesenchymal stem cell exosomes + 4 types of plant vesicles, 5 growth factors, 6 peptides, biotin and sodium hyaluronate. For hair loss and thinning; delivered by mesotherapy or microneedling. The XOMAGE line carries QR lot traceability.

$$$

ExoSignal™ Hair (Promoitalia) — hair

Italy, Promoitalia. 5 ml ampoule: synthetic exosomal structure + high-molecular-weight PDRN, 8 biomimetic peptides for the scalp, plant stem cells, vitamins, panthenol, glutathione, biotin and hyaluronic acid. 1.5–2 ml per session via microneedling; a course of at least 4 sessions at 10-day intervals, then maintenance every 2 months.

$$$

M-Exosomes Soft (Medisepte) — face, neck, décolleté, hands

Medisepte. 10 ml vial: buffalo-milk exosomes — over 0.5 billion nanoparticles per 1 ml — with sodium hyaluronate 1400–1600 kDa at 6 mg/ml. The soft, large-volume version of the M-Exosomes line for bigger areas: face, neck, décolleté, hands. A course of 4–6 sessions at 10–14 day intervals.

$$$

Purasomes SGC100+ (Skin Glow Complex) — face

Italy, Dermoaroma. AMPLEX+ technology: 20 billion bovine-colostrum exosomes and 20 growth factors plus antioxidants, peptides and plant stem cells. Radiance, even tone, recovery after inflammation. Applied through microneedling, alone or alongside another procedure.

$$$

Purasomes NC150+ (Skin Nutri Complex) — face

Italy, Dermoaroma. 20 billion colostrum exosomes and 20 biomimetic growth factors, PDRN, hyaluronic acid in two molecular weights, vitamins and amino acids. Density, firmness and structure — work on fibroblasts and collagen synthesis.

$$$

Purasomes HSC50+ (Hair & Scalp Complex) — hair

Italy, Dermoaroma. 20 billion colostrum exosomes, 200 mg across 20 growth factors, 25 mg high-molecular-weight HA (1100–1400 kDa) and 25 mg low-molecular-weight HA (80–100 kDa), 7 peptides and 8 vitamins. Resynchronises hair growth and works on the hair bulb; applied through scalp microneedling.

$$$

Exosome PDRN (MS Mesopharma) — topical

MS Mesopharma. Exosomes paired with PDRN, in 10 ml and 1500 IU vials. Topical use — this product is not injected: it is applied after microneedling, laser or a peel for recovery, hydration and a more even tone.

$$$

Course plan

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The manufacturer's protocol is one session every 14 days, four in total. The first changes in hydration and glow appear within two weeks of the first session; the cumulative effect on density and tone is assessed at the end of the course. Maintenance sessions follow your doctor's advice, usually every 2–3 months. The course combines well with RF microneedling and laser protocols: exosomal and PDRN actives are traditionally applied after device-based treatment.

Comparison

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Compared with ExoCoBio ASCE+ SRLV and BENEV the difference is fundamental and worth understanding before you choose: ExoCoBio and BENEV use cell-derived exosomes (including from umbilical stem cells), while V-Tech uses synthetic exosomal structures plus a high dose of PDRN. In terms of how it works, V-Tech sits closer to polynucleotide protocols (Rejuran, Plinest, Piennedi), but it is delivered transdermally through microneedling rather than by injection. If the goal is skin density and quality with minimal invasiveness, V-Tech is a sensible option; if cell-derived exosomes are specifically the priority, ExoCoBio or BENEV is the honest choice.

Contraindications

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⚠️ Pregnancy and breastfeeding
⚠️ Cancer
⚠️ Active autoimmune disease
⚠️ Coagulation disorders or ongoing anticoagulant therapy
⚠️ Active inflammation, pustules or herpes in the treatment area
⚠️ Individual intolerance to any component of the product

Why Paramed

Paramed

At Paramed, V-Tech System is performed by certified specialists, and before the session the doctor explains honestly what you are getting: a biomimetic system with a high dose of PDRN, not cell-derived exosomes. If ASCE+ SRLV, BENEV or injectable polynucleotides would serve your goal better, the doctor will say so — all the options are in the price list, and the choice follows the goal rather than what happens to be in stock. Storage conditions and expiry dates are strictly observed.