All treatments: Biorevitalisants
Aquashine BR and PTX (Revofil, Caregen) — boxes and syringes, Paramed Baku
Caregen Korea HA + peptides BR — pigmentation PTX — anti-aging 200–220 AZN

Aquashine BR and PTX — peptide biorevitalization in Baku

Korean peptide biorevitalizers from Caregen. Aquashine BR works on brightening and even tone in pigmentation; Aquashine PTX is an enhanced anti-aging formula with polynucleotides for mature skin.

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Overview

Aquashine is a line of biorevitalizers from the South Korean company Caregen, known for its work on biomimetic peptides. What separates it from purely hyaluronic products is that here the hyaluronic acid is the carrier while the peptides do the main work: short amino-acid chains that reproduce the signals of natural growth factors. Two versions with different jobs are available at Paramed: Aquashine BR — HA plus 5 peptides with a brightening profile, for pigmentation, dull skin and uneven tone; Aquashine PTX — HA plus peptides and polynucleotides, an enhanced formula for mature skin and density. A consultation is required; contraindications apply.

Benefits

  • Works on pigmentation and uneven tone without aggressive peels (BR)
  • Enhanced anti-aging action and skin density (PTX)
  • Signalling peptides stimulate the skin's own processes
  • Hydration and radiance from hyaluronic acid
  • Compatible with laser and device protocols for pigment

How it works

The skin is cleansed, disinfected, and a numbing cream is applied for 20–25 minutes. The product is delivered by microinjection into the superficial and mid dermis — papular technique or nappage depending on the area and the goal. A face session takes 30–40 minutes. It finishes with a soothing product and SPF, without exception.

Technology

The peptides in Aquashine work on a signalling principle: they don't substitute for growth factors but imitate their messages to cells — synthesise collagen, reduce pigment production. That's precisely why one platform yields two different products. BR uses a set of 5 peptides that influence melanogenesis — hence the brightening profile and the indications for pigmentation and uneven tone. PTX adds polynucleotides, which work on tissue regeneration and hydration, so it's more appropriate for mature skin where the goal isn't tone but density and repair. In both versions the hyaluronic acid provides hydration and distributes the actives.

  • Caregen — South Korean company, developer of biomimetic peptides
  • Peptides as signalling molecules, HA as the carrier
  • Aquashine BR: HA + 5 peptides, brightening profile
  • Aquashine PTX: HA + peptides + polynucleotides, enhanced anti-aging
  • BR — pigmentation, dull skin, uneven tone
  • PTX — mature skin, loss of density

Preparation & aftercare

Before the procedure
  • 5–7 days before — stop aspirin and ibuprofen with your doctor's approval
  • 3 days before — no active peels and no tanning
  • 24 hours before — no alcohol
  • Don't come with active inflammation, herpes, or a cold
  • Inform your practitioner about chronic conditions and lidocaine allergy
After the procedure
  • Day one — don't touch injection sites and no makeup
  • No sauna, steam room, pool for 3–5 days
  • Sleep on your back the first night
  • Use SPF 30+ for at least 2 weeks
  • No other injectable procedures for 7–10 days
  • If small bumps appear — gentle massage from 24 hours (only if your practitioner agrees)

FAQ

? What's the difference between BR and PTX?

The goal. BR has a brightening profile: pigmentation, dull skin, uneven tone. PTX is an enhanced anti-aging formula with polynucleotides: mature skin, loss of density. It isn't weaker versus stronger — they're different indications.

? Does Aquashine BR help with pigment spots?

It works on pigment production and overall tone, so it suits diffuse pigmentation and dullness. Dense localised spots usually need a combination with laser — your practitioner will assess the type of pigmentation at the consultation.

? What are peptides, and why are they better than hyaluronic acid?

They aren't better — they do something different. Hyaluronic acid retains moisture; peptides deliver signals to cells: synthesise collagen, reduce pigment production. In Aquashine both mechanisms are at work.

? How many sessions are needed?

Usually 3–4, spaced 2–3 weeks apart. For pigmentation the course is often longer and requires SPF in home care without exception.

? Will injection marks show?

Papules last 1–2 days, and small bruises are possible for up to 5 days. Plan the session about a week before any important event.

Booking

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Book a consultation — the practitioner will identify the type of concern and choose between Aquashine BR and PTX.

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Injections — mesotherapy & biorevitalization

AZN Injections — mesotherapy & biorevitalization
Service
Price
Dives BTX Lifting (mimic wrinkles)
Cocktail with hyaluronic acid and Argireline; toxin-free 'botox' effect.
280–330 AZN
PRP
Patient's autologous plasma with platelet concentrate. Universal rejuvenation of face, neck and hands; stimulates hair growth.
80 AZN
INNEA Aqua
Italy, Matex Lab. Biorevitalizer based on natural hyaluronic acid. Deep hydration, barrier restoration and skin radiance; suitable for all skin types and first-time biorevitalization.
200 AZN
Aquashine BR
Korea, Caregen. HA + 5 peptides, brightening profile. Biorevitalization for pigmentation, dull skin and uneven tone.
200 AZN
Aquashine PTX
Korea, Caregen. HA + peptides + polynucleotides. Enhanced anti-aging formula for mature skin and density.
220 AZN
Jalupro HMW
Switzerland, Professional Derma. High-molecular-weight HA + 4 amino acids (glycine, proline, lysine, leucine). Deep densification and fibroblast stimulation.
200 AZN
Restylane Vital
Sweden, Galderma. Stabilized HA via NASHA technology. Premium biorevitalization benchmark; course effect lasts up to 6 months.
300 AZN
Novacutan (Y-Bio / S-Bio)
Germany, Adoderm. Premium biorevitalization: Y-Bio (HA + 4 amino acids) or S-Bio (HA + succinic acid). Deep densification and anti-aging for face 35+. Course of 3–5 sessions.
340 AZN
RRS® HA Long Lasting
Spain, Skin Tech Pharma Group. Biorevitalizer with a high hyaluronic acid concentration plus a cocktail of vitamins, amino acids and antioxidants. Prolonged hydration, improved skin density and firmness — the effect lasts longer than standard biorevitalization. Course of 2–3 sessions spaced 3–4 weeks apart.
280 AZN
Hyalual 1.1%
Switzerland, Hyalual Institute. HA + succinic acid, entry 1.1% concentration. For sensitive skin and first-time biorevitalization.
180 AZN
Hyalual 1.8%
Switzerland, Hyalual Institute. Universal 1.8% concentration — HA + succinic acid. Standard biorevitalization for face 30+.
200 AZN
Hyalual 2.2%
Switzerland, Hyalual Institute. Maximum 2.2% HA concentration with succinic acid. Pronounced densification and anti-aging for mature skin.
230 AZN
Teosyal PureSense Redensity I
Switzerland, Teoxane. HA + 8 amino acids + 3 antioxidants + vitamin B6 + lidocaine. Biorevitalization cocktail with built-in anaesthetic for face 25–35.
250 AZN
Jalupro
Switzerland, Professional Derma. Classic HA + 4 amino acids. Base biorevitalization protocol for face 25+.
180 AZN
NCTF 135 (3 ml)
France, Filorga. 53 active ingredients — vitamins, amino acids, antioxidants, minerals, coenzymes. Classic mesotherapy for dull and dehydrated skin.
150 AZN
NCTF 135 HA (3 ml)
France, Filorga. NCTF 135 + free hyaluronic acid. Enhanced hydration combined with the full nutrient complex.
180 AZN
Dermaheal Meso HSR
Korea, Caregen. Healthy Skin Recovery — anti-aging cocktail with growth factors and peptides. Smoothness and tone for face 30+.
60 AZN
Dermaheal Meso SB
Korea, Caregen. Skin Brightening — lightening cocktail with glutathione and kojic acid. For pigmentation, melasma and dull skin.
60 AZN
Dermaheal Eyebag Solution
Korea, Caregen. Targeted cocktail for under-eye bags and puffiness. Caffeine and peptides, drainage effect.
100 AZN
Dermaheal Dark Circle Solution
Korea, Caregen. Targeted cocktail for dark under-eye circles — addresses hemosiderin and pigmentation in thin skin.
100 AZN
Dermaheal HL
Korea, Caregen. Hair Loss — scalp mesotherapy. Against hair fall, for growth stimulation and density.
60 AZN
Lipolax — lipolytic (Korea)
Korea, Lipolax. Injection lipolytic based on phosphatidylcholine + deoxycholic acid. Localised fat reduction: double chin, flanks, abdomen, knees. Course of 2–4 sessions spaced 2–3 weeks apart.
100 AZN
Lipolab — lipolytic (Caregen, Korea)
Korea, Caregen Lipolab (PPC). Phosphatidylcholine-based injection lipolytic — disrupts fat-cell membranes. Target zones: double chin, flanks, banana fold, small localised fat deposits. Course of 2–4 sessions.
100 AZN
Suisselle Cellbooster® Shape
Switzerland, Suisselle. Injectable body cocktail: hyaluronic acid + L-carnitine and a complex of actives. Targets cellulite, localised fat deposits and body skin quality — abdomen, thighs, saddlebags, arms. Course of 3–5 sessions spaced 1–2 weeks apart.
160 AZN
Exosomes for face — ExoCoBio ASCE+ SRLV
Premium flagship. Used in Oracle, Wonjin, Banobagi after laser resurfacing and microneedling.
480–550 AZN
Exosomes for face — ExoCoBio Exomage (sensitive skin, rosacea)
Anti-inflammatory profile; for rosacea, couperose and reactive skin.
500–580 AZN
Exosomes for face — BENEV
Premium; umbilical cord stem cell exosomes. Standard microneedling and RF partner.
450–520 AZN
Exosomes for face — standard kit
Accessible option for basic protocols and maintenance courses.
350–400 AZN
Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)
Original Italian PDRN from trout DNA. Skin booster for density and skin quality.
380–450 AZN
Polynucleotides (PDRN / PRDN) — Newest (Mastelli)
Reinforced Plinest formula for mature skin and areas with marked atrophy.
420–480 AZN
Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)
Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.
350–420 AZN
Polynucleotides (PDRN / PRDN) — PhilArt FACE
Standard face protocol: density, tone, post-acne, early signs of aging.
380–450 AZN
Polynucleotides (PDRN / PRDN) — Pluryal Silk
Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.
320–380 AZN
Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)
PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.
350–420 AZN
Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)
PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)
Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)
Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.
350–420 AZN
Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)
High viscosity, for post-acne scars and deep skin damage.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)
Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.
380–450 AZN
Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)
PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.
320–380 AZN
Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)
PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.
350–420 AZN
Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)
PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).
380–450 AZN
Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)
PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.
350–420 AZN

Course plan

A standard course is 3–4 sessions spaced 2–3 weeks apart. When treating pigmentation, BR is often combined with laser sessions and home care with SPF — without sun protection a tone result can't be held. Maintenance is one session every 2–3 months. Tone effects are usually visible by the 2nd–3rd session; density effects (PTX) by the end of the course.

Comparison

Against Dermaheal (also Caregen), Aquashine sits closer to biorevitalization: more hyaluronic acid and a less pronounced mesotherapy profile. Against Hyalual or Jalupro the mechanism differs fundamentally — signalling peptides instead of succinate or amino acids. For pigmentation that makes BR a more targeted choice than a general-purpose biorevitalizer. Against pure polynucleotides (Rejuran, Plinest), PTX contains them in a smaller proportion — as a component rather than the basis.

Contraindications

  • ⚠️ Pregnancy and breastfeeding
  • ⚠️ Allergy to hyaluronic acid, lidocaine, or product components
  • ⚠️ Active phase of autoimmune conditions
  • ⚠️ Oncological conditions
  • ⚠️ Blood clotting disorders
  • ⚠️ Active inflammation or herpes in the treatment area

Why Paramed

Both Aquashine versions are stocked at Paramed, and the practitioner selects the product by the type of concern rather than by availability. We use original Caregen products with controlled storage conditions and expiry dates. For pigmentation, home care and SPF are discussed separately at the consultation — without them a tone result doesn't hold, and we say so plainly.

Our doctors

Certified specialists at Paramed

All doctors →
Afa Mammadova

Afa Mammadova

Cosmetologist (MD)

27+ years' experience

1997 · Azerbaijan Medical University · +1 cert.

Languages: Russian, Azerbaijani

Simona Muradova

Simona Muradova

Cosmetologist (MD)

2019 · Yaroslavl Medical University · +1 cert.

Languages: Russian, Azerbaijani

Rena Nasibova

Rena Nasibova

Cosmetologist (MD)

25+ years' experience

1999 · Azerbaijan Medical University · +1 cert.

Languages: Russian, Azerbaijani

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