
Aybeniz Mamedli
Dermatologist (MD)
2017 · Donetsk National Medical University · +1 cert.
Languages: Russian, Azerbaijani

Filorga's French polyvitamin cocktail: 53 active ingredients in one vial. The classic of mesotherapy for dull, dehydrated skin — plus the HA version with added free hyaluronic acid.
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NCTF (New Cellular Treatment Factor) is a polyvitamin cocktail from the French laboratory Filorga and one of the most recognisable products in mesotherapy. It contains 53 active ingredients: vitamins, amino acids, minerals, coenzymes, nucleic acids and antioxidants. Its logic differs from concentrated biorevitalizers: rather than filling the skin with hyaluronic acid, NCTF creates a nutrient environment in the dermis in which fibroblasts work more actively. Two versions are available at Paramed — the base NCTF 135 and NCTF 135 HA with added free hyaluronic acid. A consultation is required; contraindications apply.
The skin is cleansed, disinfected, and a numbing cream is applied for 20–25 minutes. The product is delivered by microinjection into the superficial dermis — nappage (frequent superficial punctures) or papular technique depending on the area and the goal. A face session takes 25–35 minutes. It finishes with a soothing product and SPF.
The core idea behind NCTF is breadth, not the concentration of a single active. Its 53 ingredients cover different links in cellular metabolism: B and C vitamins as enzyme cofactors, amino acids as building material for collagen and elastin, minerals and coenzymes for cellular energy, antioxidants against oxidative stress. This kind of nutrient shower shows most clearly on dull, dehydrated, tired skin — where the problem isn't volume but the quality of metabolic processes. The 135 HA version adds free hyaluronic acid on top, so it delivers a more pronounced hydration effect and suits noticeably dry skin better.
The HA version additionally contains free hyaluronic acid. The 53-ingredient nutrient complex is identical in both, but 135 HA delivers more pronounced hydration and is preferable when the skin is noticeably dry.
Formally mesotherapy: the main action comes from the nutrient complex rather than from the volume of hyaluronic acid. The 135 HA version sits closer to biorevitalization thanks to the added HA.
Radiance and freshness are noticeable within a few days of the first session. A durable improvement in skin quality is cumulative and is assessed at the end of a 3–4 session course.
Yes — it's one of the few products that makes sense at 25–30 as prevention and for working on dull tone, without any densification agenda.
A numbing cream is applied beforehand. NCTF is considered one of the more comfortable cocktails, though sensitivity depends on the area — around the eyes it's more noticeable.
Book a consultation — the practitioner will assess your skin and decide whether the base NCTF 135 or 135 HA is the right choice.
Book a consultation →A standard course is 3–4 sessions spaced 2–3 weeks apart. NCTF is often placed first in a broader programme: level up skin quality, then move on to more concentrated biorevitalizers or device treatments. Maintenance is one session every 1–2 months. The first radiance shows within a few days; the cumulative effect builds toward the end of the course.
Against Hyalual or RRS HA Long Lasting, NCTF carries far less hyaluronic acid but a far broader nutrient profile — so it's chosen for skin quality and radiance rather than density. Against Dermaheal (Caregen's peptide cocktails), NCTF works through vitamins and amino acids rather than signalling peptides. Against Jalupro, the amino acids in NCTF come as part of a broad complex rather than in isolation. Within a single course, NCTF and a concentrated biorevitalizer are often combined.
Paramed uses the original Filorga-manufactured NCTF in 3 ml vials, with controlled storage conditions and expiry dates. At the consultation the practitioner will tell you honestly what NCTF will deliver in your case: if density and volume are the main goal, they'll suggest a more concentrated biorevitalizer, or a combination of the two within one course.
Certified specialists at Paramed

Dermatologist (MD)
2017 · Donetsk National Medical University · +1 cert.
Languages: Russian, Azerbaijani

Cosmetologist (MD)
2019 · Yaroslavl Medical University · +1 cert.
Languages: Russian, Azerbaijani

Cosmetologist (MD)
25+ years' experience
1999 · Azerbaijan Medical University · +1 cert.
Languages: Russian, Azerbaijani