Polynucleotide (PN/PDRN) Injections for Skin Repair in Baku

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Overview

Paramed

Polynucleotide (PN/PDRN) injections in Baku are Paramed's skin biorepair treatment for skin that has lost density, carries post-acne damage or is recovering after aggressive procedures. Polynucleotides are purified fragments of fish DNA that mobilise fibroblasts to rebuild collagen and elastin. Prices start at 320–380 AZN for Pluryal Silk and TwAc 1.0, while stronger formulas such as Rejuran S, Newest and Piennedi Strong cost 420–480 AZN. Several high-concentration products, including Rejuran Healer, NucleoSpire and POLY-N Strong, are priced at consultation. The doctor chooses the product by the depth of damage, not by brand name. A course is usual, and the number of sessions is set after the examination.

Benefits

Paramed

✅ A wide PN/PDRN range, from entry-level boosters to high-concentration formulas
✅ Rejuran S for post-acne scars and deep skin damage
✅ Newest and Piennedi Strong for mature skin with marked atrophy
✅ NucleoSpire for recovery after aggressive procedures
✅ Product strength chosen by a doctor after examining the skin

How it works

Paramed

1
Consultation: the doctor examines density, scars and recent procedures, and asks about fish allergy.
2
Product choice: an entry, standard or strong formula is selected for the depth of damage.
3
Preparation: no alcohol for 24 hours before; the skin is cleansed and disinfected.
4
Injection: the polynucleotide gel is placed in micro-doses across the treatment zone.
5
Course: the doctor sets the interval to the next session and when to review progress.

Technology

Paramed

PN and PDRN products are made from purified fish DNA, usually salmon or trout. Once injected, the fragments mobilise fibroblasts, which produce collagen and elastin, supporting density and repair. Concentration matters. POLY-N Strong contains 25 mg/ml, and Piennedi Strong combines PDRN 25 mg/ml with hyaluronic acid. Rejuran S has high viscosity for scars, while NucleoSpire DNA-RNA 2% adds non-stabilised hyaluronic acid for intensive revitalisation. Polynucleotides add no volume, so they are not a substitute for filler.

Pluryal Silk, TwAc 1.0 — 320–380 AZN
Plinest, Rejuran HB, TwAc 3.0 — 380–450 AZN
Rejuran S, Newest, Piennedi Strong — 420–480 AZN
Rejuran Healer, NucleoSpire, ADN Restart, POLY-N Strong — priced at consultation

Preparation & aftercare

Paramed

Before the procedure

Avoid blood thinners and alcohol for 24 hours prior to treatment.
Consult with your practitioner about any medications you are taking.
Ensure your skin is clean and free of makeup on the day of the procedure.
Stay hydrated in the days leading up to your appointment.
Discuss any allergies or skin sensitivities with your practitioner.
Arrive at the clinic on time to allow for a thorough consultation.

After the procedure

Avoid direct sunlight and tanning beds for at least a week.
Do not apply makeup for 24 hours post-treatment.
Keep the treated area clean and moisturized.
Avoid strenuous exercise for 48 hours after the procedure.
Stay hydrated to support skin recovery.
Refrain from using harsh skincare products for a week.
Follow up with your practitioner as recommended for optimal results.

Contraindications apply. A specialist consultation is required.

FAQ

Paramed

? What is PDRN skin biorepair used for? ⌄

PDRN biorepair is used for skin that has lost density and tone, for post-acne marks and scars, and for recovery after aggressive procedures. It works on skin quality through the skin's own collagen rather than by adding volume.

? Which polynucleotide is used for post-acne scars? ⌄

For post-acne scars and deep damage the doctor often chooses Rejuran S (420–480 AZN), a high-viscosity formula. Piennedi Medium (350–420 AZN) is an option for medium wrinkles and shallower scars.

? What is the difference between PN and PDRN injections? ⌄

Both terms describe purified fish-DNA fragments used as skin boosters. Plinest is Italian PDRN from trout DNA; Rejuran Healer uses salmon-DNA polynucleotides. Clinically the doctor chooses by concentration and indication, not by the label.

? Can I have polynucleotide injections with a fish allergy? ⌄

Usually not. PDRN and PN products are made from fish DNA, so an allergy to fish or salmon is a contraindication. Tell the doctor about any allergy, including to lidocaine, at the consultation.

? How much do polynucleotide injections cost in Baku? ⌄

At Paramed prices range from 320–380 AZN (Pluryal Silk, TwAc 1.0) to 420–480 AZN (Rejuran S, Newest, Piennedi Strong). Rejuran Healer, POLY-N Strong and NucleoSpire are priced at consultation.

Booking

Paramed

Ready to start?

Book a free consultation at Paramed. The doctor will assess the damage to your skin, choose a polynucleotide of the right strength and confirm the course and price.

Polynucleotides (PDRN / PRDN)

Paramed

AZN Polynucleotides (PDRN / PRDN)

Service

Price

Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)

Original Italian PDRN from trout DNA. Skin booster for density and skin quality.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Newest (Mastelli)

Reinforced Plinest formula for mature skin and areas with marked atrophy.

420–480 AZN

Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)

Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.

350–420 AZN

Polynucleotides (PDRN / PRDN) — PhilArt FACE

Standard face protocol: density, tone, post-acne, early signs of aging.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Pluryal Silk

Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.

320–380 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)

PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)

PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)

Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.

$$$

Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)

Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)

High viscosity, for post-acne scars and deep skin damage.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)

Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.

320–380 AZN

Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.

350–420 AZN

Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)

PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)

PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Elare Red PN (U-Skin Lab, Korea)

Korea, U-Skin Lab. Salmon-DNA polynucleotide skin booster. Density, tone and quality of facial skin.

350–420 AZN

Polynucleotides (PDRN / PRDN) for hair — PhilArt SCALP

Korea, Croma-Pharma. Specialized scalp protocol: microcirculation, hair thickening.

300–380 AZN

Polynucleotides (PDRN / PRDN) for hair — Plinest (Mastelli)

Italian PDRN, off-label scalp protocol. Often paired with mesotherapy and PRP.

320–400 AZN

Polynucleotides (PDRN) — ADN Restart 2% (Mesopharm)

Russia, Mesopharm. Sodium deoxyribonucleotide 2% (salmon-milt DNA fragments under 450 kDa) with tripeptide-1 and a pH 7.0 buffer, 4 ml vial. Repair and anti-ageing work; delivered by injection.

$$$

Polynucleotides (PDRN) — NucleoSpire DNA-RNA 2% (Mesopharm)

Russia, Mesopharm. Polynucleotides at 20 mg/ml (2%) as salmon-milt DNA-RNA complexes plus non-stabilised hyaluronic acid 0.3%, in 1.3 ml and 4 ml vials. Intensive revitalisation, pigmentation work and recovery after aggressive procedures.

$$$

Polynucleotides (PDRN) — POLY-N Strong (Italy)

Italy. A polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. Mobilises fibroblasts to rebuild collagen and elastin; for marked loss of density and skin quality.

$$$

Course plan

Paramed

The treatment typically involves a series of 2 to 4 sessions, spaced 2 to 4 weeks apart. This allows the skin to gradually respond to the polynucleotide injections, with noticeable improvements developing over 8 to 12 weeks.

Contraindications

Paramed

⚠️ Pregnancy or breastfeeding
⚠️ Active skin infections or inflammation
⚠️ Severe allergies to any components of the treatment
⚠️ Autoimmune diseases
⚠️ Blood clotting disorders
⚠️ Use of blood thinners or anticoagulants

Comparison

Paramed

Unlike traditional fillers that provide immediate volume, polynucleotide treatments focus on skin regeneration and long-term improvement in skin quality. This regenerative approach stimulates collagen production and enhances skin elasticity, making it a more holistic solution for skin rejuvenation.

Why Paramed

Paramed

At our clinic in Baku, we pride ourselves on using advanced technologies and high-quality products like Plinest and PhilArt. Our experienced practitioners ensure a safe and effective treatment process, and we provide thorough consultations to tailor the treatment to your specific skin needs.