Exosomes — ExoCoBio ASCE+, Exomage, BENEV for face and hair

Exosomes: ExoCoBio · Benev Mesotherapy: cocktails + HA Course of 4–6 sessions Can be combined

Exosomes vs Facial Mesotherapy — What to Choose in Baku

Mesotherapy is a 'cocktail' of vitamins, amino acids, peptides, and hyaluronic acid for skin nourishment. Exosomes are nanovesicles from stem cells carrying regeneration signals. Different technologies, different tasks, and fundamentally different costs.

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Brief Comparison

Paramed

Mesotherapy is a classic injection procedure where a 'cocktail' of vitamins (B-complex, C, K), amino acids, peptides, minerals, and often hyaluronic acid is injected into the dermis. The preparations are tailored to specific tasks: anti-aging cocktail, brightening, moisturizing. The effect is skin nourishment, improved tone and texture, and gentle stimulation of fibroblasts. Exosomes are injections of nanovesicles from stem cells that carry ready-made growth factors, cytokines, and microRNA. They do not nourish the skin with substances but 'reprogram' its cells for regeneration. Mesotherapy is cheaper and suitable as regular seasonal support. Exosomes are more expensive but provide a more powerful regenerative effect. These procedures are often combined. There are contraindications.

When to Choose What

Paramed

Mesotherapy is the first-line choice for regular care: seasonal courses in autumn/spring, supportive sessions before events, for tired and dull skin. The affordable price allows for regular treatments. Exosomes are the choice for pronounced tasks: recovery after laser procedures, post-acne with inflammation, rosacea (especially Exomage), overall skin renewal once every six months to a year. They are often combined in an annual plan: an exosome course once a year + supportive mesotherapy four times a year.

Vitamin-Amino Acid Cocktail vs Signaling Nanovesicles

Paramed

Facial mesotherapy uses multi-component cocktails: hyaluronic acid with peptides and vitamins (Aquashine, Jalupro, Restylane Vital), antioxidant complexes, amino acid mixtures. They are injected into the dermis using papule or nappage techniques and nourish the skin with necessary 'building blocks'. The effect is improved tone, color, and turgor, with gentle stimulation of fibroblasts through the peptides present in the cocktail. Exosomes are extracellular vesicles 30–150 nm from adipose tissue stem cells (ASCE+ SRLV) or umbilical stem cells (BENEV). They penetrate skin cells and deliver growth factors (TGF-β, VEGF, EGF, FGF) and microRNA, activating collagen synthesis pathways and suppressing inflammation. This is no longer 'nourishment' but signaling regeneration.

Mesotherapy: cocktail of vitamins, amino acids, peptides, HA
Exosomes: nanovesicles with growth factors and microRNA
Mesotherapy: nourishes and hydrates
Exosomes: activate regeneration at the signaling level
Mesotherapy: effect lasts 2–3 weeks, regular support
Exosomes: effect lasts 3–6 months

FAQ

Paramed

? What to choose for the first time? ⌄

If you have never had injection procedures and want to try — mesotherapy. Affordable price, instant effect on radiance, minimal downtime. Exosomes are the next level when a more powerful regenerative effect or recovery after laser/peeling is needed.

? Can they be combined? ⌄

Yes, in one protocol or separate courses. Often in an annual plan: 1 course of exosomes (3–4 sessions) + supportive mesotherapy once a month or once a season.

? What is better after laser? ⌄

Definitely exosomes. They are used immediately after fractional laser, CO2, or PiCO — they reduce the period of redness and swelling by 1.5–2 times due to their powerful anti-inflammatory action. Mesotherapy after aggressive laser is weaker.

? What lasts longer? ⌄

Exosomes — 3–6 months after the course. Mesotherapy — 2–4 weeks without support. Therefore, exosomes are done in a course 1–2 times a year, mesotherapy — regularly.

? What is better for dull skin? ⌄

If the main request is to 'revive' dull complexion in a single session, mesotherapy will provide a quick visible effect. If you want something deeper and longer-lasting — exosomes, especially in conjunction with microneedling.

Booking

Paramed

Ready to start?

Schedule a consultation at Paramed — the doctor will assess the skin condition and select a program: mesotherapy for regular support, exosomes for regeneration, or their combination.

Exosomes and Mesotherapy — Pros and Cons

Paramed

Facial Mesotherapy

Pros

Affordable price — 50–220 AZN per session
Suitable as regular seasonal support
A huge selection of cocktails for different tasks
Good effect on dull and dehydrated skin
Minimal downtime — can be done 'right before an event'

Cons

Short-term effect — regular sessions are needed
Does not work on dermal structure like PDRN or exosomes
Weak effect with pronounced atrophy
Does not help with post-acne with an inflammatory component

Exosomes (ExoCoBio ASCE+ SRLV, Exomage, BENEV)

Pros

Powerful regenerative effect
Strong anti-inflammatory action (especially Exomage)
Ideal after laser and microneedling
Visible improvement in tone and radiance — 1–2 weeks
Effect lasts 3–6 months after the course

Cons

Higher price — 350–550 AZN per session
Do not replace classic hydration
For maximum effect — better in conjunction with microneedling/laser

Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

Paramed

AZN Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

Service

Price

Dives AXC1000 (exosomes — hair or face)

Exosomal modulator: exosomes + hyaluronic acid + polynucleotides. Mesotherapy/microneedling.

200–260 AZN

ExoCoBio ASCE+ SRLV (face)

Premium flagship. Used at Oracle, Wonjin, Banobagi after laser resurfacing and microneedling.

480–550 AZN

ExoCoBio Exomage (face, sensitive skin / rosacea)

Anti-inflammatory profile; for rosacea, couperose and reactive skin.

500–580 AZN

BENEV Exosomes (face)

Premium; exosomes from umbilical stem cells. Standard partner for microneedling and RF.

450–520 AZN

Exosomes for face — standard kit

Affordable option for basic protocols and maintenance courses.

350–400 AZN

V-Tech System (Promoitalia) — face, neck, hands

Italy, Promoitalia. Synthetic exosomal structures + high-molecular-weight PDRN (20 mg/ml) + biomimetic peptides; the kit includes a mask with hyaluronic acid and plant stem cells. Applied via microneedling: face, neck, hands, feet. Protocol — 4 sessions at 14-day intervals.

$$$

RENOXOME Ultimate Rejuvenation EXO (Koru Pharma)

Korea, Koru Pharma. Exosomal skinbooster for rejuvenation: supports collagen synthesis, strengthens the extracellular matrix and filaggrin, improves elasticity, hydration and skin tone. For dull, ageing and stressed skin. Exact composition, format and protocol confirmed at consultation.

$$$

ExoCoBio ASCE for hair

Premium kit: 10 billion exosomes + biotin + 1008 growth factors. Korean flagship.

380–450 AZN

BENEV Exosomes for hair

Premium kit; exosomes from umbilical stem cells. Pairs well with microneedling and RF.

350–420 AZN

Exosomes for hair — standard kit

Affordable option for maintenance courses; alternative certified kits.

250–300 AZN

Zishel Xomage H (Korea) — hair and scalp

Korea, Zishel Medical. 10 billion particles per vial: adipose-derived mesenchymal stem cell exosomes + 4 types of plant vesicles, 5 growth factors, 6 peptides, biotin and sodium hyaluronate. For hair loss and thinning; delivered by mesotherapy or microneedling. The XOMAGE line carries QR lot traceability.

$$$

ExoSignal™ Hair (Promoitalia) — hair

Italy, Promoitalia. 5 ml ampoule: synthetic exosomal structure + high-molecular-weight PDRN, 8 biomimetic peptides for the scalp, plant stem cells, vitamins, panthenol, glutathione, biotin and hyaluronic acid. 1.5–2 ml per session via microneedling; a course of at least 4 sessions at 10-day intervals, then maintenance every 2 months.

$$$

M-Exosomes Soft (Medisepte) — face, neck, décolleté, hands

Medisepte. 10 ml vial: buffalo-milk exosomes — over 0.5 billion nanoparticles per 1 ml — with sodium hyaluronate 1400–1600 kDa at 6 mg/ml. The soft, large-volume version of the M-Exosomes line for bigger areas: face, neck, décolleté, hands. A course of 4–6 sessions at 10–14 day intervals.

$$$

Purasomes SGC100+ (Skin Glow Complex) — face

Italy, Dermoaroma. AMPLEX+ technology: 20 billion bovine-colostrum exosomes and 20 growth factors plus antioxidants, peptides and plant stem cells. Radiance, even tone, recovery after inflammation. Applied through microneedling, alone or alongside another procedure.

$$$

Purasomes NC150+ (Skin Nutri Complex) — face

Italy, Dermoaroma. 20 billion colostrum exosomes and 20 biomimetic growth factors, PDRN, hyaluronic acid in two molecular weights, vitamins and amino acids. Density, firmness and structure — work on fibroblasts and collagen synthesis.

$$$

Purasomes HSC50+ (Hair & Scalp Complex) — hair

Italy, Dermoaroma. 20 billion colostrum exosomes, 200 mg across 20 growth factors, 25 mg high-molecular-weight HA (1100–1400 kDa) and 25 mg low-molecular-weight HA (80–100 kDa), 7 peptides and 8 vitamins. Resynchronises hair growth and works on the hair bulb; applied through scalp microneedling.

$$$

Exosome PDRN (MS Mesopharma) — topical

MS Mesopharma. Exosomes paired with PDRN, in 10 ml and 1500 IU vials. Topical use — this product is not injected: it is applied after microneedling, laser or a peel for recovery, hydration and a more even tone.

$$$

c.prof 216 eyecon solution (mesoestetic) — eye contour

Spain, mesoestetic, c.prof mesoxome® line. Curcuma longa exosomes + PDRN with tranexamic acid, vitamin K1 and rutin. Dark circles, puffiness and fine lines around the eyes. Delivered transepidermally — microneedling or device-assisted systems. Format 5 × 3 ml.

$$$