Purasomes NC150+ — exosomes with PDRN for skin density, Paramed Baku

Dermoaroma, Italy 20 billion exosomes PDRN included HA in two molecular weights Price on consultation

Purasomes NC150+ (Skin Nutri Complex) — exosomes with PDRN in Baku

The richest formula in the Dermoaroma line: 20 billion colostrum exosomes and 20 growth factors, plus PDRN, hyaluronic acid in two molecular weights, vitamins and amino acids. It works on skin structure, not only on radiance.

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Overview

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Purasomes NC150+ (Skin Nutri Complex, listed by the manufacturer as Nutri Complex) is the richest product in the Dermoaroma line. The base is the same as the rest of the line: AMPLEX+ technology with 20 billion bovine-colostrum exosomes and 20 biomimetic growth factors. The difference is the nutritive half of the formula — polynucleotides (PDRN), hyaluronic acid in two molecular weights, vitamins and amino acids. That composition targets structure rather than a quick visual lift: density, firmness and the quality of the dermis. Contraindications apply and a specialist consultation is required.

Benefits

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✅ Density and firmness
✅ Stimulates fibroblasts and collagen synthesis
✅ Deep hydration from two types of HA
✅ Better dermal quality
✅ Supports skin after lasers and peels
✅ Pairs with microneedling and RF

How it works

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The skin is cleansed, disinfected and numbed for 15–20 minutes. The vial is activated before the session. The product is spread across the skin and worked in with microneedling at a depth chosen for the area and the goal. A facial session takes 40–50 minutes and finishes with a soothing product and SPF.

Technology

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The point of NC150+ is that exosomes and PDRN work at different levels and reinforce each other. Exosomes are the signal — they switch fibroblasts on. PDRN is both building material and a regeneration stimulus in its own right, familiar from products like Rejuran and Plinest. Hyaluronic acid in two molecular weights covers two jobs at once: the high-molecular-weight fraction holds water at the surface, the low-molecular-weight one works deeper. Amino acids and vitamins supply the raw material for collagen synthesis. In effect this is a hybrid of an exosome protocol and PDRN biorevitalisation in one vial, which is why NC150+ is chosen when skin has lost density rather than simply looking tired. It is applied through microneedling — the product is not injected.

Dermoaroma, Italy — AMPLEX+ technology
20 billion colostrum exosomes and 20 growth factors
PDRN (polynucleotides) in the formula
Hyaluronic acid in two molecular weights
Vitamins and amino acids
Focused on density and structure

Preparation & aftercare

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Before the procedure

No aggressive peels or resurfacing for 5–7 days beforehand
No sunbathing or solarium for 3 days
No alcohol for 24 hours
Do not come with active inflammation, herpes or an acute infection
Tell the doctor about chronic conditions and allergies, including milk protein allergy

After the procedure

Do not touch the treated area or apply make-up for the first 24 hours
Avoid sauna, steam room and pool for 3–5 days
Use SPF 30+ for at least two weeks
Postpone other injectable procedures for 7–10 days
No acids or retinol for 5–7 days

FAQ

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? How does NC150+ differ from SGC100+? ⌄

Composition and purpose. NC150+ adds PDRN, hyaluronic acid in two molecular weights, vitamins and amino acids — that is work on density and structure. SGC100+ is focused on radiance and even tone.

? Is this the same as Rejuran polynucleotides? ⌄

No. The PDRN in NC150+ is part of a complex alongside exosomes, and the product is applied through microneedling. Rejuran and Plinest are pure injectable polynucleotides at higher concentrations.

? How many sessions are needed? ⌄

Usually 3–4 at 2–4 week intervals, then maintenance every 3 months. The exact number depends on your skin.

? Does it hurt? ⌄

It depends on the microneedling depth. Numbing cream is applied beforehand and most patients describe it as tolerable tingling.

? When are results visible? ⌄

Hydration and freshness immediately; density and firmness 4–6 weeks after the last session, once collagen synthesis has completed.

Booking

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Ready to start?

Book a consultation — the doctor will assess your skin's density and choose an NC150+ protocol or an alternative.

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Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

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AZN Exosomes — ExoCoBio, BENEV, Zishel, Promoitalia

Service

Price

Dives AXC1000 (exosomes — hair or face)

Exosomal modulator: exosomes + hyaluronic acid + polynucleotides. Mesotherapy/microneedling.

200–260 AZN

ExoCoBio ASCE+ SRLV (face)

Premium flagship. Used at Oracle, Wonjin, Banobagi after laser resurfacing and microneedling.

480–550 AZN

ExoCoBio Exomage (face, sensitive skin / rosacea)

Anti-inflammatory profile; for rosacea, couperose and reactive skin.

500–580 AZN

BENEV Exosomes (face)

Premium; exosomes from umbilical stem cells. Standard partner for microneedling and RF.

450–520 AZN

Exosomes for face — standard kit

Affordable option for basic protocols and maintenance courses.

350–400 AZN

V-Tech System (Promoitalia) — face, neck, hands

Italy, Promoitalia. Synthetic exosomal structures + high-molecular-weight PDRN (20 mg/ml) + biomimetic peptides; the kit includes a mask with hyaluronic acid and plant stem cells. Applied via microneedling: face, neck, hands, feet. Protocol — 4 sessions at 14-day intervals.

$$$

ExoCoBio ASCE for hair

Premium kit: 10 billion exosomes + biotin + 1008 growth factors. Korean flagship.

380–450 AZN

BENEV Exosomes for hair

Premium kit; exosomes from umbilical stem cells. Pairs well with microneedling and RF.

350–420 AZN

Exosomes for hair — standard kit

Affordable option for maintenance courses; alternative certified kits.

250–300 AZN

Zishel Xomage H (Korea) — hair and scalp

Korea, Zishel Medical. 10 billion particles per vial: adipose-derived mesenchymal stem cell exosomes + 4 types of plant vesicles, 5 growth factors, 6 peptides, biotin and sodium hyaluronate. For hair loss and thinning; delivered by mesotherapy or microneedling. The XOMAGE line carries QR lot traceability.

$$$

ExoSignal™ Hair (Promoitalia) — hair

Italy, Promoitalia. 5 ml ampoule: synthetic exosomal structure + high-molecular-weight PDRN, 8 biomimetic peptides for the scalp, plant stem cells, vitamins, panthenol, glutathione, biotin and hyaluronic acid. 1.5–2 ml per session via microneedling; a course of at least 4 sessions at 10-day intervals, then maintenance every 2 months.

$$$

M-Exosomes Soft (Medisepte) — face, neck, décolleté, hands

Medisepte. 10 ml vial: buffalo-milk exosomes — over 0.5 billion nanoparticles per 1 ml — with sodium hyaluronate 1400–1600 kDa at 6 mg/ml. The soft, large-volume version of the M-Exosomes line for bigger areas: face, neck, décolleté, hands. A course of 4–6 sessions at 10–14 day intervals.

$$$

Purasomes SGC100+ (Skin Glow Complex) — face

Italy, Dermoaroma. AMPLEX+ technology: 20 billion bovine-colostrum exosomes and 20 growth factors plus antioxidants, peptides and plant stem cells. Radiance, even tone, recovery after inflammation. Applied through microneedling, alone or alongside another procedure.

$$$

Purasomes NC150+ (Skin Nutri Complex) — face

Italy, Dermoaroma. 20 billion colostrum exosomes and 20 biomimetic growth factors, PDRN, hyaluronic acid in two molecular weights, vitamins and amino acids. Density, firmness and structure — work on fibroblasts and collagen synthesis.

$$$

Purasomes HSC50+ (Hair & Scalp Complex) — hair

Italy, Dermoaroma. 20 billion colostrum exosomes, 200 mg across 20 growth factors, 25 mg high-molecular-weight HA (1100–1400 kDa) and 25 mg low-molecular-weight HA (80–100 kDa), 7 peptides and 8 vitamins. Resynchronises hair growth and works on the hair bulb; applied through scalp microneedling.

$$$

Exosome PDRN (MS Mesopharma) — topical

MS Mesopharma. Exosomes paired with PDRN, in 10 ml and 1500 IU vials. Topical use — this product is not injected: it is applied after microneedling, laser or a peel for recovery, hydration and a more even tone.

$$$

Course plan

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A standard course is 3–4 sessions at 2–4 week intervals, with maintenance every 3 months. NC150+ is cumulative: hydration shows immediately, while density and firmness are judged 4–6 weeks after the last session, once the fibroblasts have finished their work. It is often combined — a course of NC150+ for structure, then SGC100+ for radiance before an event.

Comparison

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Within the line the split is simple: SGC100+ for radiance and tone, NC150+ for density and structure, HSC50+ for hair. Compared with pure PDRN products (Rejuran, Plinest, PhilArt), NC150+ carries less polynucleotide but adds exosomes and growth factors, and goes in through microneedling rather than injection — which changes tolerance and downtime noticeably. If the goal is targeted work on density and post-acne scarring, the doctor may suggest injectable PDRN instead. If you want a broader formula and a gentler, needle-free protocol, NC150+ makes more sense.

Contraindications

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⚠️ Pregnancy and breastfeeding
⚠️ Allergy to the product's components, including bovine colostrum proteins
⚠️ Active-phase autoimmune disease
⚠️ Oncological disease
⚠️ Blood clotting disorders
⚠️ Active inflammation, herpes or broken skin in the treatment area

Why Paramed

Paramed

At Paramed NC150+ is chosen after an examination: if skin has lost density, the doctor explains what a course of exosomes with PDRN will do, and when injectable polynucleotides or a combination would work better. We use original Dermoaroma products with controlled storage. The price is quoted at consultation — it depends on the areas treated and the device procedure it is paired with.