All treatments: Polynucleotides (PDRN)
TwAc polynucleotide booster boxes (eyes, 2.0, 3.0) — Paramed Baku

TwAc polynucleotides (PDRN + HA) in Baku

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Overview

TwAc, made by Yuma Medical in the UK, combines PDRN with high-molecular-weight hyaluronic acid for biorevitalisation that rebuilds structure as well as hydrating. It comes in graduated strengths so intensity can be dialled to the zone and the patient's age.

Benefits

Better-hydrated, denser and more elastic skin, softened fine lines and a fresher under-eye area, with intensity matched to each zone. Well tolerated with minimal downtime.

How it works

After cleansing and optional topical numbing, the product is delivered into the dermis with fine-needle or micro-bolus technique. A session takes 20–40 minutes; you may see mild papules or redness that settle within 24–48 hours.

Technology

PDRN activates cellular repair and collagen types I and III, while the hyaluronic acid provides deep hydration and tissue support — improving density, elasticity, tone and texture together.

  • PDRN + high-molecular-weight hyaluronic acid, UK-made
  • TwAc 1.0 / 2.0 — entry and reinforced concentrations for skin quality
  • TwAc 3.0 — PDRN + HA 20 mg/ml, deformational aging, hands and décolletage
  • TwAc Eyes — under-eye dark circles, puffiness and fine lines

Preparation & aftercare

Before the procedure
  • Avoid blood thinners, alcohol and intense sun for 24–48 h before
  • Come with clean skin, no make-up in the treatment zone
  • Tell the doctor about medications and prior injectables
After the procedure
  • No make-up, sauna, pool or gym for 24 h
  • Use SPF and gentle skincare for a few days
  • Mild swelling or bruising is normal and short-lived

FAQ

? Who makes TwAc?

TwAc is produced by Yuma Medical in the United Kingdom; it combines PDRN with high-molecular-weight hyaluronic acid.

? What do the numbers 1.0 / 2.0 / 3.0 mean?

They are graduated strengths — higher numbers carry more PDRN and HA for deeper concerns and body zones.

? Is there a version for the under-eye?

Yes — TwAc Eyes is formulated for dark circles, puffiness and fine lines under the eyes.

Booking

Ready to start?

Want graduated biorevitalisation tailored to each zone? Book a consultation at Paramed in Baku to plan your TwAc course.

Polynucleotides (PDRN / PRDN)

AZN Polynucleotides (PDRN / PRDN)
Service
Price
Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)
Original Italian PDRN from trout DNA. Skin booster for density and skin quality.
380–450 AZN
Polynucleotides (PDRN / PRDN) — Newest (Mastelli)
Reinforced Plinest formula for mature skin and areas with marked atrophy.
420–480 AZN
Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)
Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.
350–420 AZN
Polynucleotides (PDRN / PRDN) — PhilArt FACE
Standard face protocol: density, tone, post-acne, early signs of aging.
380–450 AZN
Polynucleotides (PDRN / PRDN) — Pluryal Silk
Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.
320–380 AZN
Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)
PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.
350–420 AZN
Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)
PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)
Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)
Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.
350–420 AZN
Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)
High viscosity, for post-acne scars and deep skin damage.
420–480 AZN
Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)
Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.
380–450 AZN
Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)
PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.
320–380 AZN
Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)
PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.
350–420 AZN
Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)
PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).
380–450 AZN
Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)
PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.
350–420 AZN
Polynucleotides (PDRN / PRDN) — Elare Red PN (U-Skin Lab, Korea)
Korea, U-Skin Lab. Salmon-DNA polynucleotide skin booster. Density, tone and quality of facial skin.
350–420 AZN
Polynucleotides (PDRN / PRDN) for hair — PhilArt SCALP
Korea, Croma-Pharma. Specialized scalp protocol: microcirculation, hair thickening.
300–380 AZN
Polynucleotides (PDRN / PRDN) for hair — Plinest (Mastelli)
Italian PDRN, off-label scalp protocol. Often paired with mesotherapy and PRP.
320–400 AZN
Polynucleotides (PDRN) — ADN Restart 2% (Mesopharm)
Russia, Mesopharm. Sodium deoxyribonucleotide 2% (salmon-milt DNA fragments under 450 kDa) with tripeptide-1 and a pH 7.0 buffer, 4 ml vial. Repair and anti-ageing work; delivered by injection.
$$$
Polynucleotides (PDRN) — NucleoSpire DNA-RNA 2% (Mesopharm)
Russia, Mesopharm. Polynucleotides at 20 mg/ml (2%) as salmon-milt DNA-RNA complexes plus non-stabilised hyaluronic acid 0.3%, in 1.3 ml and 4 ml vials. Intensive revitalisation, pigmentation work and recovery after aggressive procedures.
$$$
Polynucleotides (PDRN) — POLY-N Strong (Italy)
Italy. A polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. Mobilises fibroblasts to rebuild collagen and elastin; for marked loss of density and skin quality.
$$$

Course plan

A standard course is 2–4 sessions spaced 2–4 weeks apart, with a maintenance session every 6–12 months. The exact plan is set at consultation based on your skin and the chosen product.

Comparison

TwAc is a PDRN + HA combo like Piennedi, so it regenerates and hydrates in one; Piennedi is Italian (Medixa), TwAc is British (Yuma Medical) and graduated by strength. Pure-PN options are Plinest (Italy) and Rejuran (Korea).

Contraindications

  • ⚠️ Pregnancy and breastfeeding
  • ⚠️ Active skin infection or inflammation in the treatment area
  • ⚠️ Autoimmune or coagulation disorders (individual assessment)
  • ⚠️ Known allergy to fish-derived products
  • ⚠️ Oncological disease without specialist clearance

Why Paramed

At Paramed in Baku the injections are performed by licensed doctors using original, certified product with traceable batch numbers. We keep the full polynucleotide range, so the choice is matched to your skin, not to stock.

Our doctors

Certified specialists at Paramed

All doctors →
Afa Mammadova

Afa Mammadova

Cosmetologist (MD)

27+ years' experience

1997 · Azerbaijan Medical University · +1 cert.

Languages: Russian, Azerbaijani

Simona Muradova

Simona Muradova

Cosmetologist (MD)

2019 · Yaroslavl Medical University · +1 cert.

Languages: Russian, Azerbaijani

Elmira Jamalova

Elmira Jamalova

Cosmetologist (MD)

2009 · Tashkent Medical Academy · +2 cert.

Languages: Russian, Azerbaijani

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