Piennedi Strong polynucleotide (PDRN + HA) box and syringe — Paramed Baku

Piennedi polynucleotides (PDRN + HA) in Baku

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Overview

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Piennedi is an Italian polynucleotide line from Medixa that combines PDRN (from salmon DNA) with hyaluronic acid in one syringe — so it regenerates and hydrates at the same time. It suits patients who want firmness plus an immediate moisture boost.

Benefits

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Firmer, denser skin with an immediate hydration boost, softened medium wrinkles and improved texture on both face and body. One product covering regeneration and moisture.

How it works

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After cleansing and optional topical numbing, the product is delivered into the dermis with fine-needle or micro-bolus technique. A session takes 20–40 minutes; you may see mild papules or redness that settle within 24–48 hours.

Technology

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The PDRN signals fibroblasts to rebuild collagen and elastin, while the hyaluronic acid gives instant hydration and support. Concentration rises across the range so treatment can be matched to skin thickness and depth of concern.

PDRN + hyaluronic acid combo, salmon-derived
Piennedi Medium — PDRN 20 mg/ml, firmness, medium wrinkles and scars
Piennedi Strong — PDRN 25 mg/ml + HA 2 mg/ml, deep regeneration
Face, neck, décolletage, hands and body zones

Preparation & aftercare

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Before the procedure

Avoid blood thinners, alcohol and intense sun for 24–48 h before
Come with clean skin, no make-up in the treatment zone
Tell the doctor about medications and prior injectables

After the procedure

No make-up, sauna, pool or gym for 24 h
Use SPF and gentle skincare for a few days
Mild swelling or bruising is normal and short-lived

FAQ

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? What is the difference between Piennedi and Plinest? ⌄

Plinest is pure PN (trout); Piennedi combines PDRN (salmon) with hyaluronic acid, adding immediate hydration to the regeneration.

? Medium or Strong? ⌄

Medium (PDRN 20) suits firmness and medium wrinkles; Strong (PDRN 25 + HA) is for deeper regeneration and body zones. The doctor decides at consultation.

? Where can Piennedi be used? ⌄

Face, neck, décolletage, the back of the hands and other body areas.

Booking

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Ready to start?

Want firmness and hydration in one step? Book a consultation at Paramed in Baku and we will pick the right Piennedi strength for your skin.

Polynucleotides (PDRN / PRDN)

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AZN Polynucleotides (PDRN / PRDN)

Service

Price

Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)

Original Italian PDRN from trout DNA. Skin booster for density and skin quality.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Newest (Mastelli)

Reinforced Plinest formula for mature skin and areas with marked atrophy.

420–480 AZN

Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)

Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.

350–420 AZN

Polynucleotides (PDRN / PRDN) — PhilArt FACE

Standard face protocol: density, tone, post-acne, early signs of aging.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Pluryal Silk

Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.

320–380 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)

PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)

PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)

Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)

Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)

High viscosity, for post-acne scars and deep skin damage.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)

Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.

320–380 AZN

Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.

350–420 AZN

Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)

PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)

PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Elare Red PN (U-Skin Lab, Korea)

Korea, U-Skin Lab. Salmon-DNA polynucleotide skin booster. Density, tone and quality of facial skin.

350–420 AZN

Polynucleotides (PDRN / PRDN) for hair — PhilArt SCALP

Korea, Croma-Pharma. Specialized scalp protocol: microcirculation, hair thickening.

300–380 AZN

Polynucleotides (PDRN / PRDN) for hair — Plinest (Mastelli)

Italian PDRN, off-label scalp protocol. Often paired with mesotherapy and PRP.

320–400 AZN

Polynucleotides (PDRN) — ADN Restart 2% (Mesopharm)

Russia, Mesopharm. Sodium deoxyribonucleotide 2% (salmon-milt DNA fragments under 450 kDa) with tripeptide-1 and a pH 7.0 buffer, 4 ml vial. Repair and anti-ageing work; delivered by injection.

$$$

Polynucleotides (PDRN) — NucleoSpire DNA-RNA 2% (Mesopharm)

Russia, Mesopharm. Polynucleotides at 20 mg/ml (2%) as salmon-milt DNA-RNA complexes plus non-stabilised hyaluronic acid 0.3%, in 1.3 ml and 4 ml vials. Intensive revitalisation, pigmentation work and recovery after aggressive procedures.

$$$

Polynucleotides (PDRN) — POLY-N Strong (Italy)

Italy. A polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. Mobilises fibroblasts to rebuild collagen and elastin; for marked loss of density and skin quality.

$$$

Course plan

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A standard course is 2–4 sessions spaced 2–4 weeks apart, with a maintenance session every 6–12 months. The exact plan is set at consultation based on your skin and the chosen product.

Comparison

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Unlike pure-PN Plinest and Rejuran, Piennedi is a PDRN + HA combo — regeneration plus instant hydration. It sits close to TwAc (also PDRN + HA); Piennedi is Italian (Medixa) and offered in Medium and Strong strengths.

Contraindications

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⚠️ Pregnancy and breastfeeding
⚠️ Active skin infection or inflammation in the treatment area
⚠️ Autoimmune or coagulation disorders (individual assessment)
⚠️ Known allergy to fish-derived products
⚠️ Oncological disease without specialist clearance

Why Paramed

Paramed

At Paramed in Baku the injections are performed by licensed doctors using original, certified product with traceable batch numbers. We keep the full polynucleotide range, so the choice is matched to your skin, not to stock.