Plinest (Mastelli) polynucleotide box — Paramed Baku

Plinest polynucleotides in Baku

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Overview

Paramed

Plinest is the original European polynucleotide, made by Mastelli in Italy from purified trout DNA. It is pure PN (no hyaluronic acid), produced with the patented PN-HPT purification, and is the reference product for regenerative skin boosting in Europe.

Benefits

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Denser, more elastic and better-hydrated skin, softened fine lines and improved under-eye quality. A well-tolerated, gradual result that suits sensitive skin and first-time patients.

How it works

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After cleansing and optional topical numbing, the product is delivered into the dermis with fine-needle or micro-bolus technique. A session takes 20–40 minutes; you may see mild papules or redness that settle within 24–48 hours.

Technology

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Plinest delivers highly purified polynucleotides into the dermis, where they hydrate, scavenge free radicals and drive fibroblasts to rebuild collagen and elastin — improving skin quality gradually and naturally.

Trout-derived PN, PN-HPT high-purity technology
Pure polynucleotide — regeneration-first, no filler effect
Plinest — face density, fine lines, early laxity
Plinest Hair — thinning scalp and early hair loss support

Preparation & aftercare

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Before the procedure

Avoid blood thinners, alcohol and intense sun for 24–48 h before
Come with clean skin, no make-up in the treatment zone
Tell the doctor about medications and prior injectables

After the procedure

No make-up, sauna, pool or gym for 24 h
Use SPF and gentle skincare for a few days
Mild swelling or bruising is normal and short-lived

FAQ

Paramed

? Is Plinest made from fish? ⌄

Yes — Plinest polynucleotides are purified from trout DNA using Mastelli's PN-HPT technology.

? Plinest or Rejuran? ⌄

Both are pure PN; Plinest is Italian (trout), Rejuran is Korean (salmon) with dedicated eye and scar variants. We help you choose at consultation.

? How soon will I see results? ⌄

Skin quality improves gradually over 8–12 weeks across a 2–4 session course.

Booking

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Ready to start?

Curious whether Plinest fits your skin? Book a consultation at Paramed in Baku and we will plan the right course and zones.

Polynucleotides (PDRN / PRDN)

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AZN Polynucleotides (PDRN / PRDN)

Service

Price

Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)

Original Italian PDRN from trout DNA. Skin booster for density and skin quality.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Newest (Mastelli)

Reinforced Plinest formula for mature skin and areas with marked atrophy.

420–480 AZN

Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)

Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.

350–420 AZN

Polynucleotides (PDRN / PRDN) — PhilArt FACE

Standard face protocol: density, tone, post-acne, early signs of aging.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Pluryal Silk

Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.

320–380 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)

PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)

PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)

Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)

Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)

High viscosity, for post-acne scars and deep skin damage.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)

Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.

320–380 AZN

Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.

350–420 AZN

Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)

PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)

PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Elare Red PN (U-Skin Lab, Korea)

Korea, U-Skin Lab. Salmon-DNA polynucleotide skin booster. Density, tone and quality of facial skin.

350–420 AZN

Polynucleotides (PDRN / PRDN) for hair — PhilArt SCALP

Korea, Croma-Pharma. Specialized scalp protocol: microcirculation, hair thickening.

300–380 AZN

Polynucleotides (PDRN / PRDN) for hair — Plinest (Mastelli)

Italian PDRN, off-label scalp protocol. Often paired with mesotherapy and PRP.

320–400 AZN

Polynucleotides (PDRN) — ADN Restart 2% (Mesopharm)

Russia, Mesopharm. Sodium deoxyribonucleotide 2% (salmon-milt DNA fragments under 450 kDa) with tripeptide-1 and a pH 7.0 buffer, 4 ml vial. Repair and anti-ageing work; delivered by injection.

$$$

Polynucleotides (PDRN) — NucleoSpire DNA-RNA 2% (Mesopharm)

Russia, Mesopharm. Polynucleotides at 20 mg/ml (2%) as salmon-milt DNA-RNA complexes plus non-stabilised hyaluronic acid 0.3%, in 1.3 ml and 4 ml vials. Intensive revitalisation, pigmentation work and recovery after aggressive procedures.

$$$

Polynucleotides (PDRN) — POLY-N Strong (Italy)

Italy. A polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. Mobilises fibroblasts to rebuild collagen and elastin; for marked loss of density and skin quality.

$$$

Course plan

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A standard course is 2–4 sessions spaced 2–4 weeks apart, with a maintenance session every 6–12 months. The exact plan is set at consultation based on your skin and the chosen product.

Comparison

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Plinest is trout-derived pure PN from Italy; Rejuran is the salmon-derived Korean equivalent with extra variants for eyes and scars. Unlike the combo products Piennedi and TwAc (PDRN + hyaluronic acid), Plinest contains no HA — pure regeneration. Newest is Mastelli's PN + HA sibling if hydration is the priority.

Contraindications

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⚠️ Pregnancy and breastfeeding
⚠️ Active skin infection or inflammation in the treatment area
⚠️ Autoimmune or coagulation disorders (individual assessment)
⚠️ Known allergy to fish-derived products
⚠️ Oncological disease without specialist clearance

Why Paramed

Paramed

At Paramed in Baku the injections are performed by licensed doctors using original, certified product with traceable batch numbers. We keep the full polynucleotide range, so the choice is matched to your skin, not to stock.