POLY-N Strong — polynucleotide gel at 25 mg/ml, Paramed Baku

Italy PDRN 25 mg/ml 2 ml syringe High concentration Price on consultation

POLY-N Strong — polynucleotides at 25 mg/ml in Baku

An Italian polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. For skin that has visibly lost density.

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Overview

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POLY-N Strong is an Italian product built on polymerised polynucleotides at 25 mg/ml, in a 2 ml syringe. That is the top of the scale: most PDRN products sit between 7.5 and 20 mg/ml. Nucleotides in the form of nucleic acids mobilise fibroblasts to rebuild collagen and elastin — skin becomes denser, texture more even, the jawline more defined. The product is biocompatible and creates no volume: it is not a filler but a stimulus for the skin's own resources. Contraindications apply and a specialist consultation is required.

Benefits

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✅ Noticeable densification
✅ Works on deformational ageing
✅ Better texture and tone
✅ Long-lasting result from a course
✅ Creates no volume — changes skin quality
✅ Pairs with laser and RF

How it works

Paramed

The skin is cleansed, disinfected and numbed for 20 minutes. The gel is placed into the mid-dermis with a linear-retrograde or papular technique, distributed carefully across the area. The session takes 30–40 minutes and finishes with a soothing product and SPF.

Technology

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A high concentration changes not just the strength of the effect but the logic of use. A dense gel spreads more slowly and stays in tissue longer, so it is chosen for areas with marked atrophy, loss of tone and a deformational ageing pattern — not for prevention at 25. The flip side is that the session is felt more than with gentle formulas like ADN Restart, and it demands careful technique: the doctor chooses depth and distribution to avoid unevenness. For the same reason POLY-N Strong is rarely used on thin under-eye skin, where less concentrated products fit better.

Italy — polymerised polynucleotides
Concentration 25 mg/ml
2 ml syringe
Mobilises fibroblasts
Rebuilds collagen and elastin
For marked loss of density

Preparation & aftercare

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Before the procedure

No aspirin or NSAIDs for 5–7 days (after agreeing it with your doctor)
No peels or sunbathing for 3 days
No alcohol for 24 hours
Do not come with active inflammation, herpes or an acute infection
Tell us about chronic conditions and allergies

After the procedure

Do not touch the injection points or apply make-up for the first 24 hours
Sauna, pool and sport after 3–5 days
SPF 30+ for at least two weeks
Other injectable procedures after 7–10 days
Drink enough water

FAQ

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? How does POLY-N Strong differ from other polynucleotides? ⌄

Concentration: 25 mg/ml against 7.5–20 mg/ml in most products. That makes it a choice for marked density loss rather than for prevention.

? Does it hurt? ⌄

It is felt more than gentle formulas — a dense gel spreads more slowly. We use numbing cream and the doctor adapts the technique to the area.

? Is it suitable for the under-eye area? ⌄

Usually not: thinner skin calls for less concentrated products. The doctor will assess at the consultation.

? How many sessions are needed? ⌄

Usually 2–3 at 3–4 week intervals, with maintenance every six months.

? Is it a filler? ⌄

No. Polynucleotides create no volume and fill no wrinkles — they stimulate fibroblasts and change skin quality.

Booking

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Ready to start?

Book a consultation — the doctor will assess your skin's density and say whether the maximum concentration is warranted.

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Polynucleotides (PDRN / PRDN)

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AZN Polynucleotides (PDRN / PRDN)

Service

Price

Polynucleotides (PDRN / PRDN) — Plinest (Mastelli, Italy)

Original Italian PDRN from trout DNA. Skin booster for density and skin quality.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Newest (Mastelli)

Reinforced Plinest formula for mature skin and areas with marked atrophy.

420–480 AZN

Polynucleotides (PDRN / PRDN) — PhilArt EYE (under-eye)

Korea, Croma-Pharma. Special formula for thin under-eye skin — dark circles, wrinkles, thinning.

350–420 AZN

Polynucleotides (PDRN / PRDN) — PhilArt FACE

Standard face protocol: density, tone, post-acne, early signs of aging.

380–450 AZN

Polynucleotides (PDRN / PRDN) — Pluryal Silk

Switzerland, MD Skin Solutions. Accessible option for basic protocols and maintenance.

320–380 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Medium (Medixa, Italy)

PDRN 20 mg/ml + hyaluronic acid. Skin density and firmness, medium wrinkles and scars.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Piennedi Strong (Medixa, Italy)

PDRN 25 mg/ml + hyaluronic acid 2 mg/ml. Deep regeneration: face, neck, décolletage, hands, body.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran Healer (PharmaResearch, Korea)

Pure polynucleotides from salmon DNA (DOT™). Flagship for all-round anti-aging, density and skin quality.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran I (under-eye) (PharmaResearch, Korea)

Formula for the periorbital area: dark circles, thin skin, under-eye wrinkles.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Rejuran S (PharmaResearch, Korea)

High viscosity, for post-acne scars and deep skin damage.

420–480 AZN

Polynucleotides (PDRN / PRDN) — Rejuran HB (PharmaResearch, Korea)

Polynucleotides + non-crosslinked hyaluronic acid. Hydration with less discomfort, good for a first course.

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc 1.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, entry concentration. Biorevitalisation and skin quality.

320–380 AZN

Polynucleotides (PDRN / PRDN) — TwAc 2.0 (Yuma Medical, UK)

PDRN + hyaluronic acid, reinforced formula. Density and tone across all skin layers.

350–420 AZN

Polynucleotides (PDRN / PRDN) — TwAc 3.0 (Yuma Medical, UK)

PDRN 10 mg/ml + hyaluronic acid 20 mg/ml. Deformational aging, hands, décolletage (30+).

380–450 AZN

Polynucleotides (PDRN / PRDN) — TwAc Eyes (under-eye) (Yuma Medical, UK)

PDRN + hyaluronic acid for the under-eye area: dark circles, puffiness, fine lines.

350–420 AZN

Polynucleotides (PDRN / PRDN) — Elare Red PN (U-Skin Lab, Korea)

Korea, U-Skin Lab. Salmon-DNA polynucleotide skin booster. Density, tone and quality of facial skin.

350–420 AZN

Polynucleotides (PDRN / PRDN) for hair — PhilArt SCALP

Korea, Croma-Pharma. Specialized scalp protocol: microcirculation, hair thickening.

300–380 AZN

Polynucleotides (PDRN / PRDN) for hair — Plinest (Mastelli)

Italian PDRN, off-label scalp protocol. Often paired with mesotherapy and PRP.

320–400 AZN

Polynucleotides (PDRN) — ADN Restart 2% (Mesopharm)

Russia, Mesopharm. Sodium deoxyribonucleotide 2% (salmon-milt DNA fragments under 450 kDa) with tripeptide-1 and a pH 7.0 buffer, 4 ml vial. Repair and anti-ageing work; delivered by injection.

$$$

Polynucleotides (PDRN) — NucleoSpire DNA-RNA 2% (Mesopharm)

Russia, Mesopharm. Polynucleotides at 20 mg/ml (2%) as salmon-milt DNA-RNA complexes plus non-stabilised hyaluronic acid 0.3%, in 1.3 ml and 4 ml vials. Intensive revitalisation, pigmentation work and recovery after aggressive procedures.

$$$

Polynucleotides (PDRN) — POLY-N Strong (Italy)

Italy. A polynucleotide gel at 25 mg/ml in a 2 ml syringe — one of the highest PDRN concentrations on the market. Mobilises fibroblasts to rebuild collagen and elastin; for marked loss of density and skin quality.

$$$

Course plan

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Usually 2–3 sessions at 3–4 week intervals — the high concentration allows fewer visits than gentle formulas require. Maintenance every 6 months. The result is judged 4–6 weeks after the last session: collagen rebuild is gradual, and an early verdict almost always understates it.

Comparison

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Within the PDRN family the difference comes down to concentration. ADN Restart 2% and NucleoSpire at 20 mg/ml are the gentle-to-middle segment, suited to a first course, thin skin and delicate areas. POLY-N Strong at 25 mg/ml is the top segment for marked density loss. Rejuran S solves similar problems through high viscosity but with a focus on post-acne scarring. If you are unsure, it is sounder to start with a less concentrated product and read the skin's response than to jump to the maximum.

Contraindications

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⚠️ Pregnancy and breastfeeding
⚠️ Allergy to fish and seafood or to the product's components
⚠️ Active-phase autoimmune disease
⚠️ Oncological disease
⚠️ Blood clotting disorders
⚠️ Active inflammation or herpes in the treatment area

Why Paramed

Paramed

At Paramed a high concentration is not prescribed by default: the doctor first assesses skin density and the ageing pattern. If a gentler formula will do the job, we say so — it is both more honest and cheaper for the patient. We work with original products; the price for POLY-N Strong is quoted at the consultation.